Fibrous Synovium Releases Higher Numbers of Mesenchymal Stem Cells Than Adipose Synovium in a Suspended Synovium Culture Model
نویسندگان
چکیده
منابع مشابه
Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis
BACKGROUND Mobilization of mesenchymal stem cells (MSCs) from the synovium was revealed using a "suspended synovium culture model" of osteoarthritis (OA). The pathology of rheumatoid arthritis (RA) differs from that of OA. We investigated whether mobilization of MSCs from the synovium also occurred in RA, and we compared the properties of synovial MSCs collected from suspended synovium culture ...
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OBJECTIVES Giant cells are commonly present in inflamed synovium, often in close association with the intimal layer. The nature of these multinucleate cells has been reassessed using new cytochemical and immunochemical techniques. METHODS Cryostat sections of non-inflamed, rheumatoid arthritic and osteoarthritic synovia were analysed for the presence of CD68 and non-specific esterase, markers...
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Synovium is specialized mesenchymal tissue that is essential for the appropriate function of the locomotor apparatus. It is the site for a series of pathologic processes that are characteristic, and in some cases specific, to this distinctive tissue. In this article, the normal microscopic anatomy of synovium is briefly reviewed. Synovial proliferative disorders, including pigmented villonodula...
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This review will describe the normal innervation of the joints, in particular the synovium, and then show how this changes in the rheumatoid arthritis (RA) joint in the human. Substance P will be described in detail, as an example of a particular neuropeptide. The concepts surrounding neuropeptide release and the role of neuropeptides in inflammatory joint disease (neurogenic inflammation) will...
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Objective: Autologous osteochondral transplantation (OCT) is an option to treat articular cartilage defects. However, poor graft integration at the cartilage defect/graft interface and secondary graft degeneration limit the use of autologous OCT. Cell sheet engineering offers hope in regenerative medicine. The purpose of this study was to evaluate the effect of synovium derived mesenchymal stem...
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ژورنال
عنوان ژورنال: Arthroscopy: The Journal of Arthroscopic & Related Surgery
سال: 2017
ISSN: 0749-8063
DOI: 10.1016/j.arthro.2016.09.033